Melatonin receptors increase Momordica’s anticancer effects against PC-3 and HT-29
نویسندگان
چکیده
Aim: The aim of our study is to the evaluation melatonin (MLT) and Momordica charantia (MC) combination on PC-3 HT-29 cancer lines address question where or not MLT increases MC antitumor effect in lines. 
 Material Method: cell were grown a manufacturer-specified culture medium. Cisplatin, MLT, increasing concentrations MC, 40 ?g/ml + applied for 72 hours. 3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyltetrazolium Bromide (MTT) viability, Total Antioxidant Capacity (TAC), Oxidant Status (TOS), Cellular Migration (Wound Healing test), Lactate Dehydrogenase (LDH) tests done hours after drug administration.
 Results: 100 µg/ml reduced viability both cells. Besides, TAC TOS levels showed correlation with LDH MTT assays found be statistically significant (P
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ژورنال
عنوان ژورنال: Journal of contemporary medicine
سال: 2021
ISSN: ['2146-6009', '2146-4189']
DOI: https://doi.org/10.16899/jcm.849993